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Elestrin

ANI Pharmaceuticals, Inc.

Drug Names(s): transdermal estradiol gel, Bio-E-Gel

Description: Once daily transdermal gel that releases estrogen for treatment of menopausal women.

Deal Structure: In June 2000, BioSante Pharmaceuticals signed an in-license agreement covering four hormone products for the treatment of testosterone deficiency in men and estrogen deficiency in women. The license agreement was signed with Permatec Technologie, AG of Switzerland. Under terms of the license agreement signed with Permatec, BioSante acquired exclusive marketing rights, with the right to grant sub-licenses, tothe three testosterone and estradiol products for all therapeutic indications in the U.S., Canada, Mexico, Israel, Australia, New Zealand, China, Malaysia, Indonesia and South Africa. BioSante will make an upfront payment, expects to fund the development of the products, make milestone payments and once regulatory approval to market is received, pay royalties on sales of the products.

Permatec, Medi-Ject and Antares
In July 2000, Medi-Ject Corporation signed a Stock Purchase Agreement with Permatec Holding AG, a privately held drug delivery company located in...See full deal structure in Biomedtracker

Partners: Antares Pharma, Inc. Mylan Inc.


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