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Drug Names(s): folate-hapten conjugate, folate-FITC
Description: EC17 is a folate-targeted hapten immunotherapy drug. Treatment consists of vaccination with EC90 (a KLH-FITC conjugate) and GPI-0100 adjuvant, followed by dosing with EC17 (folate-FITC conjugate) in combination with low-dose cytokines. The folate-FITC targets to folate-expressing cancer cells, while the KLH-FITC conjugate raises an immune response to FITC, a fluorescent small-molecule dye. By marking tumor cells with millions of folate receptor-targeted hapten, EC17 allows the body’s immune system to recognize and eliminate the cancerous cells.
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