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Daiichi Sankyo Co., Ltd.

Drug Names(s): R-161460, TRA-8, CS-1008, CS1008

Description: CS-1008 is a humanized anti-DR5 antibody. DR5 mimics the action of TRAIL and activates the apoptosis pathway. DR5 is expressed in many tumor cell lines.

Deal Structure: The compound was discovered by Sankyo and the University of Alabama and is being developed by Sankyo.

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