This web site is part of the Business Intelligence Division of Informa PLC

This site is operated by a business or businesses owned by Informa PLC and all copyright resides with them. Informa PLC’s registered office is 5 Howick Place, London SW1P 1WG. Registered in England and Wales. Number 8860726.

Elitek

Sanofi

Drug Names(s): rasburicase, SR29142, Fasturtec

Description: ELITEK (rasburicase) is a recombinant urate-oxidase enzyme produced by a genetically modifiedSaccharomyces cerevisiae strain. The cDNA coding for rasburicase was cloned from a strain ofAspergillus flavus. Rasburicase is a tetrameric protein with identical subunits of a molecular mass of about 34 kDa.

Rasburicase catalyses the conversion of uric acid to allantoin. Allantoin is an inactive metabolite of purine metabolism, and is 5 to 10 times more soluble than uric acid, so renal excretion is more effective.


Elitek News


Additional information available to subscribers only:

  • Targets
  • Routes
  • Catalysts
  • Designations
  • Events

Request a Free Demo Subscriber Login Search for another drug