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Johnson & Johnson

Drug Names(s): RWJ-445380

Description: RWJ-445380 is a cathepsin S inhibitor. Cathepsin S is a cysteine protease which is expressed in certain antigen presenting cells and has been implicated in the presentation of antigens to CD4+ T cells. Inhibition of cathepsin S may reduce antigen presentation within certain antigen presenting cells.

Deal Structure: On June 22, 2001, ALZA Corporation became a wholly owned subsidiary of Johnson & Johnson.

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