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GlaxoSmithKline plc

Drug Names(s): Aslera, Anastar, dehydroepiandrostenedione, DHEA, GL701, Prasterone

Description: The active ingredient of Prestara is Prasterone. It is the synthetic analog ofdehydroepiandrosterone (DHEA), the most abundant adrenal hormone in humans.

Deal Structure: Watson and Genelabs
In November 2000, Watson Pharmaceuticals and Genelabs Technologies entered into a collaboration and license agreement which includes marketing rights for Prestara. Watson paid Genelabs fees and milestone payments of up to $55 million, including a $10 million non-refundable initial license fee and payable milestones payments. In addition, Genelabs will receive significant royalties on net sales of and retains future co-marketing rights.

In January 2013, Watson changed its name to Actavis.

Genelabs and Tanabe Seiyaku
In January 2004, Genelabs and Tanabe Seiyaku signed a collaboration and license agreement. The agreement provided that Tanabe was responsible for conducting all development work and obtaining regulatory approval for Prestara in Japan. Under the terms of the agreement, Genelabs received an initial $2 million non-refundable license fee. In addition, $10 million of milestone payments were to be made on the achievement of...See full deal structure in Biomedtracker

Partners: Allergan plc

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