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GPCR Drug

Taisho Pharmaceutical Co., Ltd.

Drug Names(s): GPCR Drug

Description: The drug candidate is a novel oral compound. Arena and Taisho's G protein-coupled receptor (GPCR)-focused collaboration was directed toward identification studies for a receptor of interest to Taisho. Although the endogenous ligand for the unknown receptor has been previously identified, the name of the endogenous ligand has not been revealed.

Deal Structure: Under an amended agreement with Taisho, which was initially executed in May of 2000 to research a number of different GPCR targets of interest to Taisho, Taisho is responsible for development and commercialization of the drug candidate. Arena is entitled to a low single digit royalty on any product revenues received by Taisho from the sale of the drug candidate. If Taisho out-licenses the drug candidate, Arena is entitled to receive additional payments after Taisho recovers expenses associated with the research and development of the GPCR-focused projects. Arena is not entitled to any further milestone payments under the partnership.

Partners: Arena Pharmaceuticals, Inc.


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