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Biogen, Inc.

Drug Names(s): Anti-Cripto-DM4

Description: BIIB015 is a maytansinoid-conjugated monoclonal antibody with DM4 attached to it, and is directed against CRIPTO, a novel cell surface signaling molecule that is over-expressed in solid tumors.

Deal Structure: In October 2004, ImmunoGen and Biogen Idec announced that Biogen Idec licensed exclusive rights to use ImmunoGen's proprietary Tumor-Activated Prodrug (TAP) technology with antibodies to an undisclosed tumor cell target. Under the terms of the agreement, Biogen Idec received exclusive worldwide rights to develop and commercialize anticancer therapeutics that comprise an antibody developed by Biogen Idec to an undisclosed tumor cell target and a maytansinoid cell-killing agent developed by ImmunoGen. Biogen Idec will be responsible for the research, development, manufacturing, and marketing of any products resulting from the license. ImmunoGen received from Biogen Idec an upfront payment of $1 million, up to an additional $42 million if certain predetermined milestones are met, and royalties on the sales of any resultant products. ImmunoGen will also receive compensation from Biogen Idec for product development research done on its behalf, as well as for the production of preclinical...See full deal structure in Biomedtracker

Partners: ImmunoGen, Inc.

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