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Alexion Pharmaceuticals, Inc.

Drug Names(s): anti-CD200 Mab, ALXN6000

Description: ALXN6000 is a novel anti-CD200 monoclonal antibody that blocks the binding of CD200 to its receptor.

In two separate animal models of human chronic lymphocytic leukemia (CLL), administration of ALXN6000 stimulated engrafted human immune cells to attack the CD200 expressing human tumor resulting in nearly complete inhibition of tumor growth over the course of the studies.

Deal Structure: ALXN6000 is being developed in collaboration with Dyax under its Licensing and Funded Research Program.

Partners: Shire Pharmaceuticals Group PLC

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