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Elafibranor

Genfit SA

Drug Names(s): GFT-505, GFT505

Description: GFT505 is a multimodal and pluripotent medication for treatment of atherogenic dyslipidemia for an overweight patient with or without diabetes.

GFT505 is the result of a rational design process to identify a new SPPARM (Selective PPAR Modulator) based on the compatibility analysis of the structural/activity relationships for the different sub-types of PPAR receptors. GFT505 was discovered using the technical platform developed by Genfit to optimize the safety/efficacy ratio of the PPAR agonists. GFT505 is an oral treatment that acts primarily through 2 sub-types of PPAR (PPARa, PPARd) with a preferential action on PPARa.


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