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AMG 076

Amgen, Inc.

Drug Names(s): T71

Description: AMG 076 is a small molecule antagonist of the melanin concentrating hormone receptor-1 (MCHR1) receptor. MCH neurons are almost exclusively expressed in the lateral hypothalamus and project to brain areas involved in feeding, reward and mood regulation. MCHR1 antagonists are known to decrease food intake and increase energy expenditure in animals.

Deal Structure: Amgen acquired T71 on August 13, 2004 through Amgen's acquisition of Tularik.

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