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Accolate

AstraZeneca PLC

Drug Names(s): zafirlukast

Description: Accolate is an oral, selective, andcompetitive receptor antagonist of leukotriene D4 and E4 (LTD4 and LTE4), components of slow-reacting substance of anaphylaxis (SRSA). In the lung, leukotrienes are thought to be involved with increasing mucus production, airway irritability and swelling, and smooth muscle constriction. Leukotrienes are also involved in the inflammatory process.


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