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Exviera

AbbVie Inc.

Drug Names(s): ABT-333, Viekira Pak / Holkira Pak (co-packaged with dasabuvir tablets), VIEKIRA XR (dasabuvir, ombitasvir, paritaprevir and ritonavir)

Description: Our Hepatitis C revenue model includes a forecast for the combination of ABT-333, ABT-450 and ABT-267.

Historical revenues are for the Viekira Pak as a whole.

ABT-333 is an HCV non-nucleoside polymerase inhibitor.

Deal Structure: Enanta and Abbott (now AbbVie)
In December 2006, Enanta and Abbott announced a worldwide agreement to collaborate on the discovery, development and commercialization of HCV NS3 and NS3/4A protease inhibitors and HCV- protease-inhibitor-containing drug combinations. Under the agreement, Abbott is responsible for all development and commercialization activities for ABT-450. Enanta received $57 million in connection with signing the collaboration agreement, has received $55 million in subsequent clinical milestone payments, is entitled to receive $40 million in connection with regulatory filings, and is eligible to receive up to an additional $155 million in payments for regulatory and reimbursement approval milestones, as well as double-digit royalties worldwide on any revenue allocable to the collaborations protease inhibitors. Also, for any additional collaborative HCV protease inhibitor product candidate developed under the agreement, Enanta holds an option to modify the...See full deal structure in Biomedtracker

Partners: Enanta Pharmaceuticals, Inc.


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