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HSP990

Novartis AG

Drug Names(s): NVP-HSP990

Description: NVP-HSP990 is a small molecule Heat shock protein 90 (HSP90) inhibitor. HSP90 is a therapeutic target for the treatment of cancer. Proteins are the mainstay of structural and signaling elements of all cells. Hsp90 functions to stabilize and maintain the equilibrium of proteins in the cancer cell, thereby allowing a cancer cell to survive despite an abundance of misfolded and unstable proteins.

Deal Structure: Vemalis will receive from Novartis milestone payments as the compound progresses through development, and royalty payments upon commercialisation.

Partners: Vernalis Group plc


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