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Lu 02-750

H. Lundbeck A/S

Drug Names(s): Lu 02-750

Description: Lu 02-750 is a dopaminergic agent acting on brain areas affected in Parkinson's disease. In animal models, the compound has demonstrated convincing effects as compared to conventional treatments.

The precise mechanism of LU 02-750 has not been released, but Axon has patents on aporphine prodrugs (to avoid the first-pass metabolism of apomorphine) and also prodrugs with dopamine agonist, partial agonist, inverse agonist and/or antagonist effects, with mention of autoreceptors and D3 receptors.

Deal Structure: Lu 02-750 was discovered in collaboration with Groningen University and Axon Biochemicals. In September 2004, Axon Biochemicals and Lundbeck signed a collaboration agreement giving Lundbeck access to Axon's IPR on dopaminergic compounds with potential in the treatment of CNS disorders.

Partners: Axon Biochemicals B.V.


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