This web site is part of the Business Intelligence Division of Informa PLC

This site is operated by a business or businesses owned by Informa PLC and all copyright resides with them. Informa PLC’s registered office is 5 Howick Place, London SW1P 1WG. Registered in England and Wales. Number 8860726.

NOX-A12

NOXXON Pharma AG

Drug Names(s): Spiegelmer NOX-A12

Description: NOX-A12 mobilizes hematopoietic stem cells from the bone marrow by disrupting the Stromal Cell-Derived Factor-1 (SDF-1, alsoknown as CXCL12) gradient that normally attracts them to their niches. Studies in animal models demonstrate that treatment with a single dose of Spiegelmer NOX-A12 significantly mobilizes hematopoietic progenitor cells in a dose dependent manner.

Spiegelmers (L-aptamers) are chemical entities based on synthetic mirror-imageoligonucleotides which are highly selective for their pharmacological target and potent inhibitors of target function.


NOX-A12 News


Additional information available to subscribers only:

  • Targets
  • Routes
  • Catalysts
  • Designations
  • Events

Request a Free Demo Subscriber Login Search for another drug