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Allergan plc

Drug Names(s): Gaudium, Cipralex, Sipralexa, Seroplex, MLD-55, Entact

Description: Lexapro (escitalopram oxalate) is an orally administered selective serotonin reuptake inhibitor (SSRI). Lexapro is the single-active isomer of Celexa, a racemic mixture with two mirror-image halves called the S- and R-enantiomers.

Lexapro acts by inhibiting CNS neuronal reuptake of serotonin leading to increased levels of serotonin in the brain. It has little effect on norepinephrine and dopamine.

Deal Structure: Escitalopram was originally developed by Lundbeck and Forest.

Lundbeck and Mitsui
In August 2000, H. Lundbeck A/S and Mitsui Pharmaceuticals signed a semi-exclusive licence agreement on the development, registration, sale and marketing of citalopram on the Japanese market.

Lundbeck and Recordati
In January 2002, Recordati announced that it has entered into a semi-exclusive agreement with Lundbeck for the marketing and sale in Italy of escitalopram (Gaudium), indicated for the treatment of depression and panic disorders. This new agreement was reached as a follow-up to the previous license for citalopram (Elopram/Seropram), the antidepressant launched in Italy in co-marketing with Lundbeck in 1995.

In January 2014, Recordati announced that organic growth will be impacted by the termination of the license agreement for Entact (escitalopram) in Italy as a result of the products patent expiry.

Lundbeck and Mochida
In May 2002,...See full deal structure in Biomedtracker

Partners: H. Lundbeck A/S Mochida Pharmaceutical Co., Ltd. Mitsubishi Tanabe Pharma Corporation Almirall Prodesfarma, S.A. Abbott Laboratories

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