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Teva Pharmaceutical Industries Ltd.

Drug Names(s): Neutroval, XM02 filgrastim, biosimilar TevaGrastim (EU), granulocyte colony-stimulating factor (G-CSF), Granix

Description: XM02 is a granulocyte colony-stimulating factor (G-CSF) for the reduction in the duration of severe neutropenia and the incidence of febrile neutropenia in patients treated with established myelosuppressive chemotherapy for cancer. XM02 was principally developed as a similar biological medicinal product to Neupogen, the trademark for filgrastim (G-CSF).

Deal Structure: Teva developed XM02 with a partner, BioGeneriX AG, which is a 100% daughter company of ratiopharm.

In March 2010, Teva Pharmaceutical Industries announced that it entered into a definitive agreement to acquire ratiopharm for an enterprise value of 3.625 billion euros. The acquisition was completed in August 2010.

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