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Eli Lilly & Company

Drug Names(s): pemetrexed, LY231514

Description: Alimta (Pemetrexed for injection) is an antifolate antineoplastic agent that exerts its action by disrupting folate-dependent metabolic processes essential for cell replication. It main mechanism of action is the inhibition of the folate-dependent enzyme thymidylate synthase (TS) resulting in inhibition of de novo thymidylate and DNA synthesis.

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