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Drug Names(s): rimonabant, SR 141716, Acomplia

Description: The binding of endogenous ligands, such as anadamide, to cannabinoid CB1 receptors in the brain increases appetite and other cravings such as smoking. Acomplia works by blocking endogenous ligand binding to neuronal CB1 receptors.

Deal Structure: Sanofi-Aventis announced in April 2006 that it agreed with Astellas Pharma Inc. to accelerate the transfer of all rights to Acomplia in Japan from a joint-venture company held by the two groups, to Sanofi-Aventis.

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