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BVF-018

Valeant Pharmaceuticals International, Inc.

Drug Names(s): tetrabenazine modified-release (MR)

Description: BVF-018 is a modified-release formulation of tetrabenazine. Tetrabenazine is a dopamine-depleting drug that is closely related to the antipsychotics and has a similar mechanism of action. It specifically targets the vesicular monoamine transporter 2 (VMAT2). VMAT2 is located primarily in the brain and sympathetic neurons.

Deal Structure: BVF-018 was originally developed by Biovail.

Valeant and Biovail
In June 2010, Valeant and Biovail announced that both companies' Boards of Directors have unanimously approved a definitive merger agreement under which the companies would combine to generate enhanced value for stockholders. The combined company will be called Valeant Pharmaceuticals International. This acquisition closed in September 2010.


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