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Emergent BioSolutions, Inc.

Drug Names(s): Anthrax Vaccine Absorbed

Description: BioThrax is manufactured from a culture filtrate, made from a non-virulent strain of Bacillus anthracis. Anthrax bacteria produce three proteins known as protective antigen (PA), lethal factor (LF), and edema factor (EF). If the PA protein interacts with LF or EF on the surface of human or animal cells, the resultant toxins could be lethal to anyone who became infected with the bacteria. BioThrax (Anthrax Vaccine Adsorbed) stimulates the immune system to produce protective antibodies against PA. When PA is blocked, LF and EF are not able to interact with PA and the toxins are thereby neutralized.

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