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Drug Names(s): BAY94-8393, sodium clodronate
Description: Bonefos contains sodium clodronate, a bisphosphonate, which inhibits endocytic macrophages, osteoclasts, and several cancer cells through diverse mechanisms. Osteoclast inactivation results in a reduction in bone turnover, an improvement in bone mineralization, and an increase bone mass.
Deal Structure: In 2006, Bayer acquired Schering AG.
Pink Sheet Berlex’ Bonefos “Approvable”
Pink Sheet Bonefos advisory committee postponed
Pink Sheet Berlex Bonefos meeting cancelled
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