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TetraLogic Pharmaceuticals

Drug Names(s): selective SMAC mimetic, TL32711

Description: TL32711 is a synthetic, small molecule peptidomimetic of SMAC (an endogenous regulator of apoptotic cell death) that selectively antagonizes multiple Inhibitor of Apoptosis Proteins (IAPs), including XIAP, cIAP-1 and cIAP-2 and ML-IAP and cause apoptotic cell death in a broad range of tumor types.

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