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AbbVie Inc.

Drug Names(s): ABT-384

Description: ABT-384 is 11-beta-hydroxysteroid type I (HSD-1) inhibitor.

Evidence from experiments in transgenic mice and selective HSD-1 inhibitors suggest that decreasing intracellular cortisol in the hippocampus and other brain regions enhances synaptic plasticity and improves memory, including episodic memory.

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