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Effexor XR

Pfizer Inc.

Drug Names(s): venlafaxine XR, Ifekusa [JP]

Description: Effexor XR is formulated as an extended-release capsule for once-a-day oral administration. The active ingredient of Effexor, venlafaxine hydrochloride, is a structurally novel antidepressant for oral administration. Effexor is a potent inhibitor of norepinephrine and serotonin reuptake, the two neurotransmitters that are thought to play important roles in the pathophysiology of depression.

Deal Structure: Effexor XR was originally developed by Wyeth.

In January 2009, Pfizer and Wyeth announced that they entered into a definitive merger agreement under which Pfizer will acquire Wyeth in a cash-and-stock transaction currently valued at $50.19 per share, or a total of approximately $68 billion. The acquisition was completed in October 2009.

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