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Zanamivir

GlaxoSmithKline plc

Drug Names(s): intravenous zanamivir

Description: Zanamivir has been available in an inhaled form, with the trade name Relenza, since 1999. The proposed mechanism of action of zanamivir is via inhibition of influenza virus neuraminidase with the possibility of alteration of virus particle aggregation and release.

Deal Structure: Relenza was invented in Australia in the 1980s and licensed to Glaxo Wellcome by Biota Holdings Limited in 1989. This license gave to Glaxo Wellcome the rights to develop Relenza and to market the product worldwide in return for royalty payments. This royalty is 7% of net sales (except in Australia, New Zealand, Indonesia and South Africa, where it is 10%).

In April 2012, Nabi Biopharmaceuticals announced plans to merge with Biota Holdings. The execution of the merger implementation agreement will form a combined company to be named Biota Pharmaceuticals. The merger completed in November 2012.

Partners: Aviragen Therapeutics, Inc.


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