This web site is part of the Business Intelligence Division of Informa PLC

This site is operated by a business or businesses owned by Informa PLC and all copyright resides with them. Informa PLC’s registered office is 5 Howick Place, London SW1P 1WG. Registered in England and Wales. Number 8860726.

IONIS-PTP1BRx

Ionis Pharmaceuticals, Inc.

Drug Names(s): ISIS-PTP1BRx, ISIS 404173, IONIS-PTP1B Rx

Description: ISIS-PTP1BRx is an antisense drug that inhibits the production of protein tyrosine phosphatase-1B (PTP-1B), a protein that negatively regulates insulin receptor signaling. PTP-1B is responsible for turning off the activated insulin receptor, so reducing PTP-1B enhances insulin activity.


Additional information available to subscribers only:

  • Targets
  • Routes
  • Catalysts
  • Designations
  • Events

Request a Free Demo Subscriber Login Search for another drug