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Periostat MR

Galderma S.A.

Drug Names(s): Periostat SR, Col-101, doxycycline

Description: Periostat MR is a new, once-daily, modified release formulation of Periostat, CollaGenex's lead product for the treatment of adult periodontitis.

Periostat is a formulation of doxycycline, an antibiotic that disrupts protein synthesis by binding to the 30S sub-unit of the protein synthesis machinery.

Deal Structure: In February 2008, CollaGenex Pharmaceuticals announced that it entered into a definitive merger agreement with an affiliate of Galderma Pharma S.A. Upon completion of the merger, CollaGenex will become a wholly-owned subsidiary of Galderma.

In April 2008, CollaGenex became a wholly-owned subsidiary of Galderma.

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