This web site is part of the Business Intelligence Division of Informa PLC

This site is operated by a business or businesses owned by Informa PLC and all copyright resides with them. Informa PLC’s registered office is 5 Howick Place, London SW1P 1WG. Registered in England and Wales. Number 8860726.

Olipudase Alfa

Sanofi

Drug Names(s): GZ402665, Recombinant Acid Sphingomyelinase, rhASM, SAR402665

Description: Olipudase alfa is a recombinant human acid sphingomyelinase. Acid sphingomyelinases catalyze the breakdown of sphingomyelin to ceramide and phosphorylcholine. Lack of the enzyme causes Niemann–Pick disease (NPD) types A (a neuronopathic form) and B (a nonneuronopathic form).

Since olipudase does not cross the blood brain barrier, it is being developed for Niemann-Pick type B disease, where non-neurologic symptoms predominate.


Olipudase Alfa News


Additional information available to subscribers only:

  • Targets
  • Routes
  • Catalysts
  • Designations
  • Events

Request a Free Demo Subscriber Login Search for another drug