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Merck & Co., Inc.
Drug Names(s): losartan, MK0954
Description: Cozaar (Losartan) is an angiotensin II receptor antagonist. Angiotensin II, the primary vasoactive hormone of the renin-angiotensin system, is a potent vasoconstrictor. It also stimulates aldosterone secretion by the adrenal cortex. Cozaar blocks the vasoconstrictor and aldosterone-secreting effects of angiotensin II by selectively blocking the binding of angiotensin II to the AT1 receptor.
Merck reports Cozaar revenue with Hyzaar. Please see Hyzaar's page for historical revenue.
Deal Structure: Effective January 1991, Merck and E. I. du Pont de Nemours and Company (Du Pont) entered into a joint venture to form a worldwide pharmaceutical company for the research, marketing, manufacturing and sale of pharmaceutical and imaging agent products. Under separate agreements between Merck and Du Pont for which the joint venture carries out Du Pont's obligations, commencing in 1993 marketing applications were submitted worldwide for Cozaar and Hyzaar.
Partners: E. I. du Pont de Nemours and Company
Pink Sheet Cozaar Paragraph IV Certification
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