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Eli Lilly & Company

Drug Names(s): Abciximab, C7E3 Fab.

Description: REOPRO (Abciximab) is an antithrombotic that inhibits platelet aggregation. REOPRO is the Fab fragment of the chimeric human-murine monoclonal antibody 7E3 that binds to the glycoprotein (GP) IIb/IIIa receptor of human platelets and inhibits platelet aggregation. Abciximab also binds to the vitronectin (avb3) receptor found on platelets and vessel wall endothelial and smooth muscle cells.

Partners: Johnson & Johnson

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