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Drug Names(s): REN-1654
Description: REN-1654 reduces inflammation in the nervous system by decreasing the release of tumor necrosis factor a (TNFa), a signaling molecule used by the immune system and certain cells in the nervous system. During inflammation, TNFa is thought to play a key role both in directly causing an increase in pain signaling and in damaging nerves by increasing the inflammatory response.
Deal Structure: This compound was originally developed by Renovis. In September 2007, Evotec AG and Renovis announced that they have entered into a definitive agreement under which Evotec will acquire Renovis. This acquisition was closed in May 2008.
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