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GlaxoSmithKline plc

Drug Names(s): Cefuroxime axetil

Description: Ceftin is a semisynthetic, broad-spectrum second generation cephalosporin antibiotic for oral administration. Compared to first generation cephalosporins such as Keflex, second generation cephalosporins exhibit better Gram-(-) activity and somewhat weaker Gram-(+) activity. They are more stable to Gram-(-) beta lactamases. They exhibit good activity against many enteric Gram-(-) rods, Haemophilus influenzae, and Neisseria gonorrheae; moderate activity against streptococci and staphylococci; and poor activity against enterococci, methacillin resistant Staphylococcus aureus and Psuedomonas.

As with all cephalosporins, Ceftin inhibits bacterial cell wall synthesis by inhibiting penicillin binding proteins.

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