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Human Parthenogenetic Stem Cells

International Stem Cell Corporation

Drug Names(s): hpSCs, hPNSC (neural), ISC-hpNSC

Description: Parthenogenetic stem cells are derived from parthenogenetically activated human oocytes. Parthenogenetic activation of metaphase II (MII) oocytes with a combination of the activating agents ionomycin and 6-dimethylaminopurine (6-DMAP) block the extrusion of the 2nd polar body, therefore activated oocytes retain all of their genetic material. The HLA genotypes of stem cells derived from these oocytes are heterozygous and genetically matched to the donors.

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