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KX02

Athenex, Inc.

Drug Names(s): KX2-361, KX-02

Description: KX02 is a lipophilic dual src/pretubulin inhibitor discovered and developed by Kinex Pharmaceuticals. It is a small molecule that has shown potent inhibitory activity against a broad panel of brain tumor cell lines, including cells (T98G) that are resistant to Temodar, the most widely used chemotherapy for the treatment of malignant glioma.

Deal Structure: Kinex and Xiangxue
In May 2012, Kinex and Xiangxue entered into a license agreement regarding KX02.

Under the terms of the agreement, Xiangxue will acquire the rights to the development and commercialization of KX02 for all oncology indications in greater China, including China, Hong Kong, Taiwan, and Singapore. Xiangxue will assume all development responsibility and associated costs in the licensed territory and will collaborate with Kinex during this process. Xiangxue will provide Kinex with an up-front payment, development milestone payments and royalties associated with product sales.

Partners: Guangzhou Xiangxue Pharmaceutical Co., Ltd.


KX02 News


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