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AC Immune, Ltd.

Drug Names(s): ACI-24

Description: ACI-24 is a liposome-based vaccine with tetra-palmitoylated amyloid beta 1-15 peptide.

ACI-24 has been developed from AC Immune’s SupraAntigen Platform and is designed to act as an active vaccine stimulating the patient's immune system to produce beta-sheet conformation-specific antibodies that prevent plaque deposition or enhance clearance of plaques. During preclinical development, the ACI-24 has shown high efficacy in vivo by memory restoration and plaque reduction. The vaccine is also characterized by a very high specificity due to generating a conformation-specific antibody response. The favorable safety profile of ACI-24 is underlined through the absence of local inflammation in relevant models as well as its T-cell independent mechanism shown in preclinical development.

ACI-24 News

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