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CAT-3888

AstraZeneca PLC

Drug Names(s): recombinant immunotoxin BL22, GCR-3888

Description: CAT-3888 is an immunotoxin fusion protein consisting of an anti-CD22 disulfide-linked Fv antibody fragment and the exotoxin PE38 from Pseudomonas. CAT-3888 is designed to bind and kill cancer cells that express CD22 on their surface.

Deal Structure: Cambridge Antibody Technology (CAT) announced in November 2005 the acquisition of GCR-3888 from Genencor. The consideration for the acquisition is up to $16 million, of which $14 million will be paid by CAT on closing. Simultaneously, Genencor will subscribe $14 million for 1,170,277 new CAT ordinary shares (representing 2.27 percent of CAT's existing issued share capital).

In June 2006, CAT became a subsidiary of AstraZeneca.

Partners: Danisco A/S


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