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2-Iminobiotin

Neurophyxia B.V.

Drug Names(s): 2-IB

Description: 2-Iminobiotin (2-IB) is a biotin (Vitamin H or B7) analogue and selective nitric oxide synthase (NOS) inhibitor. Nitric oxide (NO) plays a critical role in the development of perinatal asphyxia. Its synthesis occurs through three nitric oxide synthase (NOS) iso-enzymes, two of which can be inhibited selectively by 2-IB.


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