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Drug Names(s): 2-IB
Description: 2-Iminobiotin (2-IB) is a biotin (Vitamin H or B7) analogue and selective nitric oxide synthase (NOS) inhibitor. Nitric oxide (NO) plays a critical role in the development of perinatal asphyxia. Its synthesis occurs through three nitric oxide synthase (NOS) iso-enzymes, two of which can be inhibited selectively by 2-IB.
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