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Drug Names(s): CTX4430, EP-501, CTX-4430
Description: CTX-4430 is a small molecule inhibitor of Leukotriene A4 Hydrolase (LTA4H), the pivotal enzyme for synthesis of the potent pro-inflammatory molecule Leukotriene B4 (LTB4). It has both high oral uptake and potent inhibition of LTA4H across several rodent and non-rodent species.
Celtaxsys and Estrellita
In January 2012, Celtaxsys acquired CTX-4430 (formerly EP-501) from Estrellita Pharmaceuticals.
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