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Johnson & Johnson

Drug Names(s): JNJ42756493, JNJ-493

Description: JNJ-42756493 is a pan-fibroblast growth factor receptor (FGFR) tyrosine kinase inhibitor.

Deal Structure: Astex and Janssen
In June 2008, Astex and Janssen entered into a research alliance focused on the research, development and commercialisation of novel drugs for the treatment of cancer. The new agreement grants Janssen a worldwide exclusive license to compounds arising from Astexs novel FGFR inhibitor program, and the parties are also to establish a new drug discovery alliance focused on the identification of novel inhibitors against a further two cancer drug targets. Under the terms of the agreement, Ortho Biotech Research & Development, the research and development arm of Janssen, will be responsible for completing all of the pre-clinical and clinical development of all products arising from the collaboration and for their commercialisation globally. The agreement also grants Astex an option to co-commercialise FGFR products developed under the collaboration in the USA.

Astex and Otsuka
In September 2013, Otsuka and Astex announced that their respective...See full deal structure in Biomedtracker

Partners: Otsuka Holdings Co., Ltd.

JNJ-42756493 News

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