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NK4 (Gene Therapy)
Kringle Pharma, Inc.
Drug Names(s): NK4 (Gene Therapy)
Kringle is developing NK4 as a gene and protein therapy.
NK4 is a competitive antagonist of the HGF/cMet interaction. It is composed an N-terminal hairpin domain and four K-domains from HGF. Thus, it contains the cMet receptor binding domain but lacks biological activity. That is, it displaces HGF binding to cMet receptor but does not activate the receptor.
NK4 (Gene Therapy) News
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