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NI-105

Biogen, Inc.

Drug Names(s): NI 105

Description: NI-105 is an antibody targeted against alpha-synuclein.

Deal Structure: In December 2010, Biogen Idec and Neurimmune Holding AG announced that Biogen Idec has acquired a subsidiary of Neurimmune, which includes the world-wide rights to three pre-clinical immunotherapy programs. The three programs are focused on the discovery and development of novel human antibodies that address three central nervous system (CNS) targets: alpha-synuclein, tau and TDP-43. Biogen Idec will make an initial payment of $32.5 million and up to $395 million in contingent payments.

Biogen Idec will be responsible for the development of the pre-clinical candidates and the commercialization of all products. Neurimmune will be responsible for additional scientific activities with respect to the lead candidates as well as the discovery of back-up candidates, utilizing its Reverse Translational Medicine technology platform. Neurimmune retains the right to use its platform for creating therapeutic antibody products outside the scope of its agreement with Biogen Idec.

Partners: Neurimmune Holdings AG


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