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Eli Lilly & Company
Drug Names(s): LY2157299, 4-[2-(6-methylpyridin-2-yl)-5,6-dihydro-4H-pyrrolo[1,2-b]pyrazol-3-yl]-quinoline-6-carboxamide monohydrate
Description: LY2157299 is an inhibitor of TGF-beta receptor 1 kinase. TGF-beta overexpression affects the tumor microenvironment by decreasing immune surveillance, increasing tumor invasiveness and metastatic potential, and enhancing angiogenesis.
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