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ACH-3422

Johnson & Johnson

Drug Names(s): ACH-3422

Description: ACH-3422 is a nucleotide prodrug of uridine analog designed to inhibit HCV NS5B polymerase. Studies have shown that ACH-3422 enables the conversion of the prodrug into its monophosphate within the liver.

Deal Structure: Achillion and Janssen
In May 2015, Achillion entered into a worldwide license and collaboration arrangement with Janssen to develop and commercialize one or more of Achillion's lead hepatitis C virus (HCV) assets which include ACH-3102, ACH-3422, and sovaprevir.

Under the terms of the agreement, Achillion will grant Janssen an exclusive, worldwide license to develop and, upon regulatory approval, commercialize HCV products and regimens containing one or more of Achillion's HCV assets. Achillion is eligible to receive a number of payments based upon achievement of specified development, regulatory and sales milestones. Achillion is also eligible to receive tiered royalty percentages between mid-teens and low-twenties based upon future worldwide sales. Janssen will be responsible for all of the development costs within the collaboration and all subsequent costs related to commercialization of the HCV assets.

Additionally, in an equity transaction separate to...See full deal structure in Biomedtracker

Partners: Achillion Pharmaceuticals, Inc.


ACH-3422 News


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