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AstraZeneca PLC

Drug Names(s): AZD6140, ticagrelor, Brilique (EU), Possia (EU)

Description: Brilinta is an oral, reversible agent that inhibits platelet aggregation through blocking the adenosine diphosphate (ADP) receptor. This prevents ADP-mediated activation of the glycoprotein GPIIb/IIIa complex.

Deal Structure: Brilinta was originally developed by AstraZeneca.

AstraZeneca and Merck
In February 2008, AstraZeneca announced that Merck has elected not to exercise the First Option related to the relinquishment of Mercks rights over the products not covered by the Partial Retirement of AstraZenecas and Mercks 1982 agreement. Products covered by the First Option include Entocort, Atacand and Plendil, and certain products still in development, including Brilinta, AZD3355, AZD6765 and AZD2327.

In March 2010, AstraZeneca notified Merck that it will exercise the First Option related to the relinquishment of Merck's rights to royalty payments from certain products in the United States. The Second Option regarding Prilosec and Nexium is exercisable by AstraZeneca in 2012, or in 2017, or if combined annual sales of the two products fall below a minimum amount.

AstraZeneca and The Medicines Company
In April 2012, AstraZeneca entered into an agreement with The Medicines Company...See full deal structure in Biomedtracker

Partners: The Medicines Company

Brilinta News

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