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ABT-165

AbbVie Inc.

Drug Names(s): ABT-165

Description: ABT-165 is a dual-variable domain immunoglobulin that targets VEGF and DLL4. DLL4 is a notch pathway ligand involved in angiogenesis and maintenance of tumor stem cells. The dual activity of ABT-165 is designed to address the emerging clinical challenge of tumor resistance to anti-VEGF therapies.


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