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Fragmin

Eisai Co., Ltd.

Drug Names(s): dalteparin

Description: Fragmin is a low molecular weight heparin. Like heparin, Fragmin prevents blood clots from forming. It works by blocking the action of two of the 12 proteins in blood (factors X and to a lesser degree factor II) whose action is necessary in order for blood to clot. It acts mainly by accelerating the rate of the neutralization of coagulation factors by antithrombin, but other mechanisms may also be involved.

Deal Structure: In September 2005, Eisai signed an in-license agreement with Pfizer for exclusive U.S. rights to promote FRAGMIN. Eisai also will assume responsibility for post-marketing studies and product distribution, as well as book all U.S. sales. According to this agreement, Pfizer will transfer the New Drug Application for FRAGMIN to Eisai for the duration of the deal.

Partners: Pfizer Inc.


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