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Naftopidil

Asahi Kasei Corporation

Drug Names(s): Flivas (Korea)

Description: Naftopidil (Flivas) is a selective 1-adrenergic receptor antagonist or alpha blocker. Naftopidil (Flivas) is also an antihypertensive agent and binds specifically to alpha 1-adrenoceptors. Naftopidil relaxes aortic strips precontracted with norepinephrine concentration-dependently, and naftopidil (Flivas) shifts the concentration-response curve of norepinephrine in a parallel manner to the right.

Deal Structure: In April 2009, Asahi Kasei Pharma and Dong-A concluded a license agreement granting Dong-A exclusive rights for the development and sale of Flivas in Korea. Dong-A obtained approval from the Korea Food and Drug Administration (KFDA) as an agent for the treatment of BPH in April 2011.

Partners: Dong Wha Pharmaceutical Ind. Co.


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