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PEG sTNF-RI

Amgen, Inc.

Drug Names(s): Pegsunercept

Description: PEG sTNF-RI is a recombinant version of naturally-occuring soluble tumor necrosis factor receptor I, a cytokine playing a fundamental, complex role in various inflammatory processes. Among its many actions is its ability to reduce the inflammatory effects of TNFa.

The recombinant protein is conjugated to polyethylene glycol (PEG) to extend its half-life after injection, a strategy that Amgen has used successfully with Neulasta.


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